Scientific Studies

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Scientific Evidence

Explore the latest peer-reviewed studies validating the benefits of our key ingredients, organized by health category.

Shilajit

Modulates Stress Response in Animal Model (2012)

Ingredient: Shilajit standardized to DBPs, DCPs & fulvic acid

Study Type: Animal model (stress-induced chronic fatigue in rats)

Key Findings: Reversed stress-induced behavioral changes, normalized corticosterone levels, preserved adrenal gland weight, and protected mitochondrial function—indicating HPA axis modulation and antioxidant protection.

Evidence Level: Preclinical – Animal

Reference: PubMed – Behavioral Brain Research, 2012

Shilajit

Stress Relief via Magnesium (2025)

Ingredient: Shilajit rich in magnesium

Study Type: Health article summary

Key Findings: Magnesium in Shilajit may help relieve anxiety by reducing cortisol levels and calming the nervous system.

Evidence Level: Observational – Needs more human studies

Reference: Cleveland Clinic, 2025

Shilajit

Bone Density in Postmenopausal Women

Ingredient: Shilajit (standardized aqueous extract)

Study Type: Randomized, double-blind, placebo-controlled trial

Key Findings: Supplementation with 250 mg or 500 mg of Shilajit extract daily for 48 weeks resulted in dose-dependent preservation of bone mineral density (BMD) in the lumbar spine and femoral neck. The study also observed reductions in markers of bone turnover, oxidative stress, and inflammation.

Evidence Level: Human – Clinical

Reference: PubMed – Andrologia, 2016

Shilajit

Testosterone & Sexual Function (2016)

Ingredient: Purified Shilajit

Study Type: Randomized controlled trial

Key Findings: Supplementation for 90 days significantly increased total testosterone, free testosterone, and DHEAS levels in healthy men, along with improved sexual function scores.

Evidence Level: Human – Clinical

Reference: PubMed – Andrologia, 2016

Shilajit

Combat Fatigue & Boost Physical Performance (2016)

Ingredient: Standardized Shilajit (PrimaVie®)

Study Type: Human clinical trial (NCT02026414)

Key Findings: Improved skeletal muscle adaptation, physical performance, and reduced fatigue in overweight individuals.

Evidence Level: Human clinical data – Moderate

Reference: International Journal of Basic & Clinical Pharmacology, 2016

Moringa

Immune & Nutritional Benefits in HIV Adults (2025)

Ingredient: Moringa oleifera supplementation

Study Type: Systematic review & meta-analysis

Key Findings: Significant increases in CD4+ T cell counts, white blood cells, platelets, and BMI—indicative of improved immune and nutritional status.

Evidence Level: Human – Systematic review/meta-analysis

Reference: Frontiers in Nutrition, 2025

Moringa

Nutrition Powerhouse & Anti-Inflammatory (2023)

Ingredient: Moringa oleifera leaves, seeds, pods

Study Type: Review of nutritional profile

Key Findings: Extremely nutrient-dense—packed with protein, vitamins (especially A & C), minerals, and antioxidants; shows potential for reducing oxidative stress and inflammation.

Evidence Level: General review – Preclinical & observational

Reference: Healthline – Moringa Benefits

Citrus Pectin

Metabolic Syndrome in Rats (2024)

Ingredient: Citrus pectin (20% in high-fat diet)

Study Type: Animal in vivo

Key Findings: Reduced body weight, fat accumulation, improved insulin resistance, and lower leptin levels—likely by delaying gastric emptying and enhancing satiety.

Evidence Level: Preclinical – Animal

Reference: PubMed, 2024

Pectin

Digestive Health & Gut Microbiome (Human, 4-Week Trial)

Ingredient: Pectin, 24 g/day

Study Type: Human clinical trial

Key Findings: Improved stool consistency, reduced constipation, and increased populations of beneficial gut bacteria in 80 participants.

Evidence Level: Human – Clinical

Reference: Healthline – Pectin Benefits

Low-Methoxy Citrus Pectin

Anxiety & Inflammation in Humans (2024)

Ingredient: Low-methoxy citrus pectin (LM pectin)

Study Type: Human pilot study

Key Findings: At 20 g/day, reduced pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, INF-γ), increased anti-inflammatory IL-10, and lowered anxiety scores vs control.

Evidence Level: Human – Pilot clinical

Reference: Citrus pectin may reduce anxiety and inflammation

MCT Oil

Memory in Older Adults (2022)

Ingredient: MCT supplementation

Study Type: Systematic review of RCTs

Key Findings: Improved working memory in 4 of 6 studies, especially in those with lower baseline cognition; more research needed for dose optimization.

Evidence Level: Human – Systematic RCT review

Reference: BioMed Central – MCT Oil and Memory

MCT

Cognitive Effects in MCI Subjects (2015)

Ingredient: MCT oil, 56 g/day for 24 weeks

Study Type: Randomized controlled trial (n=6)

Key Findings: Raised ketone levels and improved memory vs placebo in mild cognitive impairment.

Evidence Level: Human – Pilot RCT

Reference: PubMed – MCT and MCI

MCT Oil

Alzheimer’s Disease (6-Month Trial, 2022)

Ingredient: MCT oil (42 g/day)

Study Type: Randomized, double-blind, placebo-controlled crossover + open-label extension

Key Findings: 80% of participants remained stable or improved in MMSE and Cognigram scores; longer use and age >73 linked with greater gains.

Evidence Level: Human – RCT

Reference: PubMed – MCT and Alzheimer's

MCT & Lipid Profile

(2021 Meta-Analysis)

Ingredient: MCT oil

Study Type: Meta-analysis of RCTs

Key Findings: No significant effects on total cholesterol, LDL, or HDL; slight increase in triglycerides. Effects varied based on control fat type.

Evidence Level: Human – Meta-analysis

Reference: MCT oil